MOTS-c
Supports metabolism, exercise capacity, and healthy cellular aging. A mitochondrial-derived peptide that activates AMPK, your cells' energy-balancing switch.
Pairs with 3 recommended supplements
MOTS-c activates AMPK from inside the mitochondria; Berberine activates it from the cell membrane. This is dual-pathway AMPK activation, the body's metabolic master switch turned on from two angles simultaneously, producing greater improvements in glucose uptake, fat oxidation, and insulin sensitivity than either alone.
MOTS-c activates mitochondrial metabolism, CoQ10 is the electron carrier at the center of the electron transport chain making that possible. As MOTS-c ramps up mitochondrial output, CoQ10 demand rises in proportion. Supplementing CoQ10 prevents it from becoming the limiting factor in the cellular energy production MOTS-c drives.
Increased mitochondrial activity generates reactive oxygen species as a byproduct. Alpha-Lipoic Acid is a mitochondria-specific antioxidant that neutralizes these at the source, protecting the mitochondria during elevated output. It also enhances insulin signaling, adding a third angle of glucose metabolism improvement alongside MOTS-c.